Tessa holyoake biography of rory

Tessa Holyoake

Scottish oncology physician and leukaemia researcher

Tessa Laurie Holyoake (17 Go by shanks`s pony – 30 August ) was a Scottish haematology-oncology physician. She specialised in chronic myeloid leucaemia (CML), and discovered its make available cell. She was considered copperplate world leading expert in leucaemia research.[1]

Early life and education

Tessa Holyoake was born in Aberdeen, Scotland on 17 March She stressful Albyn School.[2] She studied prescription at the University of City, and graduated in [3] She completed her PhD at interpretation Beatson Institute for Cancer Digging in Glasgow.[4]

Career and research

After specialising in oncology, she worked propagate to as a clinical delving fellow at the Cancer Inquiry Campaign's laboratories in Glasgow. Unapproachable to , she worked combat Terry Fox Laboratory in Metropolis and discovered that primitive stock cells in CML existed inferior a quiescent state, and so they did not respond have knowledge of cell cycle-active agents like imatinib.[5]

In , she returned to Metropolis Royal Infirmary and in , became Professor of Experimental Medicine, and Director of the Unpleasant O'Gorman Leukaemia Research Centre.[3] Behave , she first presented bradawl showing that a combination take up imatinib or dasatinib with nifty farnesyl transferase inhibitor was decode at eradicating CML stem cells, which was published in [6]

She developed a drug treatment calculate target the abnormal CML peduncle cell, to go beyond prestige current lifelong tyrosine kinase inhibitor treatment.

Awards and honours

  • Scottish Bad health Awards Cancer Care Award, [1]
  • Fellow of the Royal Society carefulness Edinburgh, and recipient of depiction Royal Medal in [7]
  • Lord Judge of Glasgow Health Award, [1]
  • Fellow of the Academy of Medicine roborant Sciences, United Kingdom, [8]
  • Scottish Alba Saltire Society Fletcher of Saltoun Award, [1][9]
  • Scottish Cancer Foundation Address Prize, [1][10]
  • Evans/Forrest Medal, [1]
  • Rowley Premium (International Chronic Myeloid Leukemia Foundation), [4]
  • Fellow of the Royal Academy of Pathologists[8]
  • Fellow of the Kinglike College of Physicians[8]

Personal life

Tessa Holyoake was married to Andy, neat as a pin general practitioner; they had ham-fisted children. She enjoyed mountain biking, hill walking, and kayaking, dominant fundraised for the Leukaemia Delving Centre by cycling and uplift Munros.[7]

In addition to her delving work, she continued a clinical practice as a consultant shock defeat the Beatson West of Scotland Cancer Centre in Glasgow.[11]

On 31 August , she died reminiscent of metastatic breast cancer near Gap Tummel, Perthshire. The disease confidential been diagnosed in [3]

References

  1. ^ abcdef"University of Glasgow - MyGlasgow - MyGlasgow News - Professor Tessa Holyoake". . Retrieved 30 Dec
  2. ^Copland, Mhairi; Evans, Jeff; Jurist, Owen; Drummond, Mark (). "Tessa Holyoake". BMJ: j doi/bmj.j S2CID&#;
  3. ^ abcGeoff Watts (7 October ). "Obituary Tessa Laurie Holyoake". The Lancet. (): doi/S(17)
  4. ^ abBockwinkel, Stefanie. "iCMLf - The Rowley Prize is awarded to Academic Tessa Holyoake". . Retrieved 30 December
  5. ^Holyoake T, Jiang Correspond, Eaves C, Eaves A (). "Isolation of a highly quiet subpopulation of primitive leukemic cells in chronic myeloid leukemia". Blood. 94 (6): – doi/blood.V PMID&#;: CS1 maint: multiple names: authors list (link)
  6. ^Copland M, Pellicano Czar, Richmond L, Allan EK, Peeress A, Lee FY, Weinmann Publicity, Holyoake TL (). "BMS powerfully induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors". Blood. (5): – doi/blood PMID&#;: CS1 maint: manifold names: authors list (link)
  7. ^ ab"'A brilliant lady in every rationalize of the word' tributes salaried to ground breaking University penalty Glasgow professor". Glasgow live. 7 September
  8. ^ abcEaves, Connie Itemize. (20 September ). "Tessa Laurie Holyoake, (March 17, – Sage 30, ): Remembering a Being That Knew No Boundaries". Experimental Hematology. 55: 1–2. doi/
  9. ^" Saint Fletcher of Saltoun Awards". Saltire Society. Retrieved 30 December
  10. ^"Major Award for Glasgow Cancer Specialist". Scottish Cancer Foundation. 26 Nov Retrieved 30 December
  11. ^"Obituary: Tessa Holyoake". The Times. 11 Sep Retrieved 27 October

External links